Endocrine Abstracts

A 37-year-old female was referred with recurrent episodes of altered consciousness and disorientation. She described a three-year history of recurrent “funny turns”. They started with a sensation of warmth accompanied with cold sweat followed by unfamiliarity with the surroundings and cognitive impairment. The attacks increased in frequency gradually over time. There was a tendency for the attacks to occur in the morning, before bed and 3–4 hours after food. The...

We report a 49 year-old female patient who was referred to the endocrine clinic with two months history of heat intolerance and weight loss. She denied any symptoms related to her eyes. Past medical history included hypertension, epilepsy and manic-depressive psychosis, and she was on lithium, atenolol, phenobarbitone, doxazosin and phenytoin. On examination, there was a 45 g firm symmetrical multi-nodular goitre (MNG) with normal examination of both eyes. Thyroid function tes...

Introduction: Evaluation and management of thirst and polyuric syndromes can be challenging in endocrine practice.Case report: A 24-year old lady presented with weight loss, thirst, polyuria, vomiting and abdominal pain. She had acromegaly treated by transsphenoidal surgery 5 years ago. Medications included hydrocortisone, thyroxine (T4), the oral contraceptive pill as well as bromocriptine for postoperative acromegaly. Examination revealed postural hyp...

Introduction and aims: The role of screening for thyroid disease in diabetes (DM) remains controversial. We assessed the prevalence of thyroid dysfunction on first screening in a population of patients with diabetes who previously had thyroid function tests (TFT) only on clinical suspicion.Methods: TFT and thyroid peroxidase antibodies (TPO) were measured in 236 consecutive patients with DM (mean age 59±13 years, type1 16%, type2 84%, female 48%)...

Introduction: Riedel's thyroiditis is a rare chronic inflammatory disease of the thyroid characterised by an invasive fibrotic process.Case report: A 48-year old lady with newly diagnosed profound hypothyroidism was started on thyroxine and referred due to a rapidly enlarging goitre. Examination revealed a hard fixed goitre in an euthyroid patient. Thyroglobulin (titre 1: 10,000) and thyroid peroxidase (titre 1: 100,000) antibodies were strongly positiv...

Background and aims: Cardiovascular (CVS) disease accounts for the majority of morbidity and mortality in diabetes. We audited lipid management in a hospital diabetes clinic.Patients: CVS disease risk factors were assessed in 241 consecutive patients with diabetes (type1 15%, type2 85%, male 53%, female 47%, mean age 59±13 years, mean duration of diabetes 10±9 years). 86(36%) had symptomatic atherosclerotic vascular disease (secondary prev...

Introduction: Hypocalcemia in post-operative hypoparathyroidism responds to oral vitamin D and calcium replacement. We describe a case of persistent symptomatic hypocalcemia and hypothyroidism despite oral replacement and management with supervised weekly supplementation.Case history: A 56-year-old lady had total thyroidectomy for multinodular goitre. Persistent post-operative hypoparathyroidism and hypothyroidism necessitated replacement with calcitriol...

Polycystic ovarian syndrome (PCOS) is a common disorder affecting women of childbearing age. The clinical triad of PCOS includes: hirsuitism, oligo/amenorrhoea and ultrasonographic appearances of PCOS. However, this triad could occur in other disorders such as late onset congenital adrenal hyperplasia (CAH). Although CAH is mainly diagnosed in childhood, it could occur in adults. In this abstract we describe a patient who presented with features of PCOS, the final diagnosis, h...